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Antigenic Specificity | Mouse SCF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Stem cell factor (SCF), also known as c-kit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Mature mouse SCF consists of a 189 amino acid (aa) extracellular domain (ECD), a 23 aa transmembrane segment, and a 36 aa cytoplasmic tail. The ECD shows both N-linked and O-linked glycosylation. Proteolytic cleavage at two alternate sites in the extracellular juxta-membrane region releases a 25 kDa soluble molecu |
Immunogen | Immunogen: Recombinant mouse SCF (RT #M30-025). Preparation: Produced from sera of rabbits pre-immunized with highly pure (>95%) recombinant mouse SCF (Lys26-Ala189) derived from E. coli. |
Other Names | [mouse SCF; Mast cell growth factor; Stem cell factor; c-Kit ligand], [Kitl; Kitlg; Gb; SF; Sl; Clo; Con; Mgf; SCF; SLF; blz; Kitlg; contrasted; Kitl; Mgf; Sl; Slf; MGF; SCF; sKITLG] |
Gene, Accession # | [SCF], Gene ID: 17311, NCBI: NP_038626.1, UniProt: P20826 |
Catalog # | MBS691099 |
Price | $295 |
Order / More Info | Mouse SCF Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Sette et al, Int J Dev Biol 44 (2000) 2. Kapur et al, Blood 100 (2002) 3. Bashamboo et al, J Cell Sci 119 (2006) 4. Huang et al, Cell 63 (1990) 5. Arakawa et al, J Biol Chem 266 (1991) 6. Majumdar et al, J Biol Chem 269 (1994) 7. Brannan et al, Proc Natl Acad Sci (1991) 8. Flanagan et al, Cell 64 (1991) 9. Martin et al, Cell 63 (1990) |