ZIC1/2/3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityZIC1/2/3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total ZIC1/2/3 protein. Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3' By similarity.Yokota N., Cancer Res. 56:377-383(1996).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human ZIC1/2/3.
Other Names[Zinc finger protein ZIC 1; Zinc finger protein of the cerebellum 1; ZIC1]
Gene, Accession #[ZIC1/2/3], Gene ID: 7545, NCBI: NP_003403.2, UniProt: Q15915
Catalog #MBS9410853
Price$200, $255
Order / More InfoZIC1/2/3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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