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Antigenic Specificity | ZIC1/2/3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ZIC1/2/3 protein. Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3' By similarity.Yokota N., Cancer Res. 56:377-383(1996). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human ZIC1/2/3. |
Other Names | [Zinc finger protein ZIC 1; Zinc finger protein of the cerebellum 1; ZIC1] |
Gene, Accession # | [ZIC1/2/3], Gene ID: 7545, NCBI: NP_003403.2, UniProt: Q15915 |
Catalog # | MBS9410853 |
Price | $200, $255 |
Order / More Info | ZIC1/2/3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |