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Antigenic Specificity | SET / TAF-I IHC-plus |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | chicken, bovine, mouse, rat, human, monkey |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human SET. SET Antibody, 2PP2A Antibody, HLA-DR-associated protein II Antibody, I-2PP2A Antibody, TAF-IBETA Antibody, SET nuclear oncogene Antibody, TAF-I Antibody, Template-activating factor I Antibody, I2PP2A Antibody, IGAAD Antibody, IPP2A2 Antibody, PHAPII Antibody, Protein SET Antibody Description: Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone chaperoning. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL)-induced apoptosis, GZMA cleaves SET, disrupting its binding to NME1 and releasing NME1 inhibition. Isoform 1 and isoform 2 are potent inhibitors of protein phosphatase 2A. |
Immunogen | Immunogen Description: Synthetic peptide Ac-LNSNHDGADETSEKEQC (Human SET, 13-28 a. a.). Immunogen Type: Synthetic peptide |
Other Names | [Rabbit (IgG) to Human SET / TAF-I; Human SET / TAF-I; 2PP2A; HLA-DR-associated protein II; I-2PP2A; TAF-IBETA; SET nuclear oncogene; Template-activating factor I; I2PP2A; IGAAD; IPP2A2; PHAPII; Protein SET], [SET; SET; 2PP2A; IGAAD; TAF-I; I2PP2A; IPP2A2; PHAPII; TAF-IBETA; IGAAD; I-2PP2A; TAF-I] |
Gene, Accession # | [SET / TAF-I], Gene ID: 6418, NCBI: NP_003002.2, UniProt: Q01105 |
Catalog # | MBS249982 |
Price | $530 |
Order / More Info | SET / TAF-I IHC-plus Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |