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Antigenic Specificity | DMTF1 (C-term), 588-616 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.3 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DMTF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-616 amino acids from the C-terminal region of human DMTF1. This gene encodes a transcription factor that contains acyclin D-binding domain, three central Myb-like repeats, and twoflanking acidic transactivation domains at the N- and C-termini.The encoded protein is induced by the oncogenic Ras signalingpathway and functions as a tumor suppressor by activating thetranscription of ARF and thus the ARF-p53 pathway to arrest cellgrowth or induce apoptosis. It also activates the transcription ofaminopeptidase N and may play a role in hematopoietic celldifferentiation. The transcriptional activity of this pro |
Immunogen | n/a |
Other Names | [Cyclin-D-binding Myb-like transcription factor 1; hDMTF1; Cyclin-D-interacting Myb-like protein 1; hDMP1; DMTF1; DMP1] |
Gene, Accession # | [DMTF1], Gene ID: 9988, NCBI: NP_001135798.1, UniProt: Q9Y222 |
Catalog # | MBS9203680 |
Price | $165, $370 |
Order / More Info | DMTF1 (C-term), 588-616 Antibody from MYBIOSOURCE INC. |
Product Specific References | Liu, Y., et al. Mol. Psychiatry (2010) In press : Sugiyama, T., et al. Expert Rev. Mol. Diagn. 8(4):435-447(2008) Inoue, K., et al. Cancer Res. 68(12):4487-4490(2008) Tschan, M.P., et al. Leukemia 22(5):1087-1090(2008) Mallakin, A., et al. Cancer Cell 12(4):381-394(2007) |