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Antigenic Specificity | NCSTN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 429-669 of human NCSTN (NP 056146.1). |
Other Names | [ATAG1874] |
Gene, Accession # | [NCSTN], Gene ID: 23385, NCBI: Q92542.2, UniProt: Q92542 |
Catalog # | MBS8549477 |
Price | $280 |
Order / More Info | NCSTN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |