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Antigenic Specificity | KDM2A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, horse, sheep, rabbit, dog, chicken |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: KDM2A Antibody detects endogenous levels of KDM2A. Description: Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis.S |
Immunogen | Immunogen: A synthesized peptide derived from human KDM2A. Tissue Specificity: Widely expressed, with highest levels in brain, testis and ovary, followed by lung. |
Other Names | [[Histone-H3]-lysine-36 demethylase 1A; CXXC-type zinc finger protein 8; CXXC8; F box/LRR repeat protein 11; F box and leucine rich repeat protein 11; F box protein FBL7; F-box and leucine-rich repeat protein 11; F-box protein FBL7; F-box protein Lilina; F-box/LRR-repeat protein 11; FBL11; FBL7; FBXL11; JHDM1A; JmjC domain-containing histone demethylation protein 1A; Jumonji C domain containing histone demethylase 1A; kdm2a; KDM2A_HUMAN; LILINA; Lysine (K) specific demethylase 2A; Lysine-specific demethylase 2A] |
Gene, Accession # | [KDM2A], Gene ID: 22992, NCBI: NP_036440.1, UniProt: Q9Y2K7 |
Catalog # | MBS9611856 |
Price | $240, $280 |
Order / More Info | KDM2A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |