Mitofusin 2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMitofusin 2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentration0.6 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionEssential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein respon
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 543-593 on human Mitofusin 2 protein. Immunoglobulin: IgG. Expression: Ubiquitous; expressed at low level. Highly expressed in heart and kidney.
Other Names[CMT2A; CMT2A2; CPRP 1; EC 3.6.5.-; Fzo; HSG; hyperplasia suppressor gene; Hypertension related protein 1; KIAA0214; MARF; MFN 2; Mitochondrial assembly regulatory factor; Mitofusin-2; Transmembrane GTPase MFN2], [MFN2; MFN2; HSG; MARF; CMT2A; CPRP1; CMT2A2; HMSN6A; CPRP1; KIAA0214]
Gene, Accession #Gene ID: 9927, NCBI: NP_055689, UniProt: O95140
Catalog #MBS542100
Price$390
Order / More InfoMitofusin 2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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