Edit |   |
---|---|
Antigenic Specificity | ERalpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ERalpha Polyclonal Antibody detects endogenous levels of ERalpha protein. ESR1 encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein (estrogen receptor 1) localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript |
Immunogen | Immunogen: Synthesized peptide derived from human ERalpha around the non-phosphorylation site of S167 |
Other Names | [Rabbit ERalpha; ESR1; ESR; NR3A1; Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1] |
Gene, Accession # | [ERalpha], Gene ID: 2099, NCBI: NP_000116.2, UniProt: P03372 |
Catalog # | MBS9702010 |
Price | $130, $220, $325 |
Order / More Info | ERalpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |