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Antigenic Specificity | RNF5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD; the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the 'Lys-48'-linked polyubiquitination of TMEM173 at 'Lys-150' leading to its proteasomal degradation; the ubiquitination occurrs in mitochondria after viral transfection and regulates |
Immunogen | Immunogen: Recombinant human E3 ubiquitin-protein ligase RNF5 protein (N-120AA) |
Other Names | [E3 ubiquitin-protein ligase RNF5; Protein G16; RING finger protein 5; Ram1 homolog; HsRma1; RNF5; G16; NG2; RMA1] |
Gene, Accession # | [RNF5], Gene ID: 6048, NCBI: NP_008844.1, UniProt: Q99942 |
Catalog # | MBS7046293 |
Price | $120, $160 |
Order / More Info | RNF5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |