LRP1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLRP1
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formatunconjugated
Size0.02 mL, 0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Flow Cytometry (FC/FACS)
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DescriptionThis gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients.
ImmunogenSource Note: This monoclonal antibody is produced by immunizing animals with a polypeptide corresponding to LRP1 protein.
Other Names[Prolow-density lipoprotein receptor-related protein 1], [CD91]
Gene, Accession #[LRP1], Gene ID: 4035, NCBI: NP_002323.2, UniProt: Q07954
Catalog #MBS435213
Price$225, $350, $565
Order / More InfoLRP1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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