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Antigenic Specificity | MYT1 (PKMYT1) (C-term), 452-482 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MYT1 (PKMYT1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-482 amino acids from the C-terminal region of human MYT1 (PKMYT1). The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoform |
Immunogen | n/a |
Other Names | [Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; Myt1 kinase; PKMYT1; MYT1] |
Gene, Accession # | [PKMYT1], Gene ID: 9088, NCBI: NP_001245379.1, UniProt: Q99640 |
Catalog # | MBS9211208 |
Price | $165, $370 |
Order / More Info | MYT1 (PKMYT1) (C-term), 452-482 Antibody from MYBIOSOURCE INC. |
Product Specific References | Dai, X., et al., J. Invest. Dermatol. 122(6):1356-1364 (2004). Nakajima, H., et al., J. Biol. Chem. 278(28):25277-25280 (2003). Passer, B.J., et al., Proc. Natl. Acad. Sci. U.S.A. 100(5):2284-2289 (2003). Okumura, E., et al., Nat. Cell Biol. 4(2):111-116 (2002). Booher, R.N., et al., J. Biol. Chem. 272(35):22300-22306 (1997). |