ClEC9A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityClEC9A
Clone[ABM23H8]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1 kappa
FormatProtein G purified
Size0.025 mg, 0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionCLEC9A is a C-type lectin receptor involved in the sensing and presentation of antigens derived from necrotic cells. It is expressed on the surface of the mouse and human dendritic cell subsets specialized for the uptake and processing of material from dead cells. CLEC9A is expressed at the cell surface as a glycosylated dimer and can mediate endocytosis, but not phagocytosis. It possesses a cytoplasmic immunoreceptor tyrosine-based activation-like motif that can recruit Syk kinase and can induce proinflammatory cytokine production. CLEC9A provides targeted recruitment of the adaptive immune system during infection and can also be utilized to enhance immune responses generated by vaccines.
ImmunogenImmunogen Information: A partial length recombinant protein (a.a 15-218) of CLEC9A was used as the immunogen for this antibody.
Other Names[C-type lectin domain family 9 member A; CLEC9A], [CLEC9A; CLEC9A; CD370; DNGR1; DNGR-1; UNQ9341]
Gene, Accession #[ClEC9A], Gene ID: 283420, NCBI: Q6UXN8.1, UniProt: Q6UXN8
Catalog #MBS668311
Price$145, $290
Order / More InfoClEC9A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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