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Antigenic Specificity | IL23 Receptor Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Interleukin 23 receptor is a type I cytokine receptor. IL23R is its human gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.Protein Function: Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute resp |
Immunogen | Immunogen: E Coli-derived mouse IL23 Receptor recombinant protein (Position: I25-D233). Subcellular Localization: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed by Th1, Th2 and dendritic cells. |
Other Names | [Interleukin-23 receptor; IL-23 receptor; IL-23R; Il23r] |
Gene, Accession # | [Il23r], Gene ID: 209590, NCBI: NP_653131.2, UniProt: Q8K4B4 |
Catalog # | MBS1750445 |
Price | $280 |
Order / More Info | IL23 Receptor Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |