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Antigenic Specificity | HDAC5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Direct ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for HDAC5 detection. Tested with WB, IHC-P, Direct ELISA in Human; Mouse; Rat.Background: Histone deacetylase 5, also called HDAC5 or KIAA0600, is an enzyme that in humans is encodes by the HDAC5 gene. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. This gene is mapped to 17q21.31. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family membe |
Immunogen | Immunogen: E Coli-derived human HDAC5 recombinant protein (Position: H102-E197). |
Other Names | [Histone deacetylase 5; HD5; Antigen NY-CO-9; HDAC5; KIAA0600] |
Gene, Accession # | [HDAC5], Gene ID: 10014, NCBI: NP_001015053.1, UniProt: Q9UQL6 |
Catalog # | MBS1751317 |
Price | $315 |
Order / More Info | HDAC5 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. McKinsey, T. A., Zhang, C.-L., Lu, J., Olson, E. N. Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation. Nature 408: 106-111, 2000. 2. Potthoff, M. J., Wu, H., Arnold, M. A., Shelton, J. M., Backs, J., McAnally, J., Richardson, J. A., Bassel-Duby, R., Olson, E. N. Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers. J. Clin. Invest. 117: 2459-2467, 2007. |