PA26 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPA26
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionSpecificity: PA26 Polyclonal Antibody detects endogenous levels of PA26 protein. SESN1 encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The sestrin 1 mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
ImmunogenImmunogen: Synthesized peptide derived from the internal region of human PA26 at AA rangle: 240-320
Other Names[Rabbit PA26; SESN1; PA26; SEST1; Sestrin-1; p53-regulated protein PA26]
Gene, Accession #[PA26], Gene ID: 27244, NCBI: NP_001186862.1, UniProt: Q9Y6P5
Catalog #MBS9705188
Price$130, $220, $325
Order / More InfoPA26 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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