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Antigenic Specificity | PATZ1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1; 22)(p36.1; q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene |
Immunogen | Immunogen: Recombinant protein of human PATZ1 (NP 114440.1). |
Other Names | [POZ-, AT hook-, and zinc finger-containing protein 1 long C isoform; POZ-, AT hook-, and zinc finger-containing protein 1; POZ-, AT hook-, and zinc finger-containing protein 1; POZ/BTB and AT hook containing zinc finger 1; BTB/POZ domain zinc finger transcription factor; Protein kinase A RI subunit alpha-associated protein; Zinc finger and BTB domain-containing protein 19; Zinc finger protein 278; Zinc finger sarcoma gene protein] |
Gene, Accession # | [PATZ1], Gene ID: 23598, NCBI: NP_055138, UniProt: Q9HBE1 |
Catalog # | MBS8566240 |
Price | $280 |
Order / More Info | PATZ1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |