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Antigenic Specificity | SFRS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total SFRS1 protein. SF2/ASF is a member of the Ser-Arg-rich (SR) protein family of highly conserved nuclear phosphoproteins involved in pre-mRNA splicing (1). Besides its role in nuclear pre-mRNA splicing, SF2/ASF has been shown to shuttle between the nucleus and cytoplasm, suggesting additional roles in mRNA transport and cytoplasmic events (2). SF2/ASF associates with translating ribosomes and stimulates translation (3). It also activates translation initiation by suppressing the activity of 4E-BP1, which is mediated by SF2/ASF association with mTOR and the phosphatase PP2A (4). More recent studies have demonstrated a role for SF2/ASF in microRNA processing (5). |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human SFRS1. |
Other Names | [ASF; MGC5228; SF2; SF2p33; SRp30a] |
Gene, Accession # | [SFRS1], Gene ID: 6426, NCBI: NP_001071634.1, UniProt: Q07955 |
Catalog # | MBS9407396 |
Price | $255 |
Order / More Info | SFRS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |