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Antigenic Specificity | CD163 |
Clone | [MRQ-26] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 5 Control Slides, 0.1 mL (Concentrate), 3 ml (Prediluted) |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD163 is a 130 kDa membrane glycoprotein. CD163 was recently identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. Solubilized in plasma, CD163 functions as an anti-inflammatory signal and has many roles in disease processes that range from autoimmune conditions such as Rheumatoid Arthritis to Atherosclerosis. CD163 is expressed exclusively on the cell surface of human monocytes and macrophages that evolve predominantly in the late phase of inflammation, and is, therefore, very useful for macrophage-phenotyping. This receptor is expressed on the surface of monocytes (low expression) and histiocytes (high expression). Staining for CD163 has been helpful |
Immunogen | n/a |
Other Names | [CD163; Scavenger receptor cysteine-rich type 1 protein M130; Hemoglobin scavenger receptor], [CD163; M130] |
Gene, Accession # | [CD163], UniProt: Q86VB7 |
Catalog # | MBS370129 |
Price | $130, $190, $225 |
Order / More Info | CD163 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |