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Antigenic Specificity | Human Apoptosis-stimulating of p53 protein 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42. |
Immunogen | Immunogen: Recombinant human Apoptosis-stimulating of p53 protein 2 protein (360-600aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10922 / sc-10924 / sc-10920 |
Other Names | [Bcl2-binding protein; Bbp; Renal carcinoma antigen NY-REN-51; Tumor suppressor p53-binding protein 2; 53BP2; p53-binding protein 2; p53BP2; TP53BP2; ASPP2; BBP], [TP53BP2; TP53BP2; BBP; 53BP2; ASPP2; P53BP2; PPP1R13A; ASPP2; BBP; Bbp; 53BP2; p53-binding protein 2; p53BP2] |
Gene, Accession # | [TP53BP2], Gene ID: 7159, NCBI: NP_001026855.2, UniProt: Q13625 |
Catalog # | MBS1494228 |
Price | $120, $160 |
Order / More Info | Human Apoptosis-stimulating of p53 protein 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |