(Mouse) Dnmt1 (Center) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | (Mouse) Dnmt1 (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MouseDnmt1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 881-914 amino acids from the Central region of mouse Dnmt1. Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In association with DNMT3B and |
| Immunogen | n/a |
| Other Names | [DNA (cytosine-5)-methyltransferase 1; Dnmt1; Met-1; DNA methyltransferase MmuI; DNA MTase MmuI; MMmuI; MCMT; Dnmt1; Dnmt; Met1; Uim] |
| Gene, Accession # | [Dnmt1], Gene ID: 13433, NCBI: NP_001186360.2, UniProt: P13864 |
| Catalog # | MBS9213109 |
| Price | $165, $370 |
| Order / More Info | (Mouse) Dnmt1 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Bestor T.H.,et al.J. Mol. Biol. 203:971-983(1988). Yoder J.A.,et al.J. Biol. Chem. 271:31092-31097(1996). Aguirre-Arteta A.M.,et al.Cell Growth Differ. 11:551-559(2000). Margot J.B.,et al.J. Mol. Biol. 297:293-300(2000). Mertineit C.,et al.Development 125:889-897(1998). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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