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Antigenic Specificity | GSKIP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 0.96mg/mL |
Applications | Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. |
Immunogen | Immunogen: Fusion protein of human GSKIP |
Other Names | [C14ORF129; Chromosome 14 open reading frame 129; GSK3-beta interaction protein; GSK3beta interaction protein; GSKIP; GSKIP; MGC4945; UPF0279] |
Gene, Accession # | [GSKIP], Gene ID: 51527, NCBI: NP_001258833.1, UniProt: Q9P0R6 |
Catalog # | MBS2560783 |
Price | $110, $150, $225 |
Order / More Info | GSKIP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |