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Antigenic Specificity | Cytokeratin 13 |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human, Cattle, rat |
Isotype | n/a |
Format | unconjugated |
Size | 5 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Formalin/Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cytokeratin 13 is an acidic filament protein, which especially exprimed in squamous epithelia. Therefore it is found in exocervix, vagina, oral mucosa, tongue, oesophage, epidermis and urothelium. The CK13 antibody mainly reacts with squamous epithelia and squamous cell carcinoma. Cytokeratins are a group of water soluble filament proteins, which are components of the cytoskeleton of the epidermis and other epithelial cells. Gel-electrophoretic investigation revealed 20 different Cytokeratins, characterised by different molecular sizes and pI-values. They can be subdivided into basic and acid subfamilies. The nomenclature according to Moll et al. (1982) is most commonly used. Acid Cytokeratin 13, 54 kD, pI 5.1. |
Immunogen | Immunogen: Human purified Cytokeratin 13 |
Other Names | [cytokeratin 13; Keratin, type I cytoskeletal 13; keratin, type I cytoskeletal 13; keratin 13; Cytokeratin-13; CK-13; Keratin-13; K13], [KRT13; KRT13; K13; CK13; WSN2; CK-13; K13] |
Gene, Accession # | Gene ID: 3860, NCBI: CAA36673.1, UniProt: P13646 |
Catalog # | MBS397093 |
Price | $470 |
Order / More Info | Cytokeratin 13 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Moll R., Franke W.W., Schiller D.L., Geiger B., and Krepler R. (1982) The Catalog of Human Cytokeratins: Patterns of Expression in Normal Epithelia, Tumors and Cultured Cells. Cell 31; 11 ff. 2. Sun T.-T. Tseng S.C.G., Huang A.J.W., Cooper D., Lynch M.H., Weiss R., Eichner R., and Schermer (1985) Monoclonal antibody studies of keratin expression: A review. In: Intermediate Filaments, Wang E. et al. eds. N.Y. Acad. Sci. 455, pp 307 ff. 3. Petzoldt JL, Leigh IM, Duffy PG, Masters JR (1994) Culture and characterisation of human urothelium in vivo and in vitro. Urol Res;22(2):67-74. 4. Rugg E, Magee G, Wilson N, Brandrup F, Hamburger J, Lane E (1999) Identification of two novel mutations in keratin 13 as the cause of white sponge naevus. Oral Dis 5(4):321-324. 5. De La Rosette J., Smedts F., Schoots C., Hoek H., and P. Laguna (2002) Changing patterns of keratin expression could be associated with functional maturation of the developing human bladder. J. Urol. 168(2); 709-717. |