DELE Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDELE
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
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DescriptionDELE Antibody: DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-α and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-α, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.
ImmunogenImmunogen: DELE antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human DELE. Buffer: DELE Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[DELE; DELE; DELE; Death ligand signal enhancer; KIAA0141], [KIAA0141; KIAA0141; DELE; DELE]
Gene, Accession #[KIAA0141], Gene ID: 9812, NCBI: NP_055588, UniProt: Q14154
Catalog #MBS151106
Price$375
Order / More InfoDELE Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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