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Antigenic Specificity | DELE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DELE Antibody: DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-α and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-α, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors. |
Immunogen | Immunogen: DELE antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human DELE. Buffer: DELE Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [DELE; DELE; DELE; Death ligand signal enhancer; KIAA0141], [KIAA0141; KIAA0141; DELE; DELE] |
Gene, Accession # | [KIAA0141], Gene ID: 9812, NCBI: NP_055588, UniProt: Q14154 |
Catalog # | MBS151106 |
Price | $375 |
Order / More Info | DELE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |