Edit |   |
Antigenic Specificity | HE4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg |
Concentration | n/a |
Applications | ELISA Detection (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for HE4 detection. Tested with ELISA(Det) in Rat.Background: WAP four-disulfide core domain protein 2, also known as Human Epididymis Protein 4 (HE4), is a protein that in humans is encoded by the WFDC2 gene. This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be i |
Immunogen | Immunogen: E Coli-derived rat HE4 recombinant protein (Position: E31-F168). Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
Other Names | [WAP four-disulfide core domain protein 2; WAP four-disulfide core domain 2; WAP four-disulfide core domain protein 2; Epididymal secretory protein 4; RE4; Wfdc2] |
Gene, Accession # | [HE4], Gene ID: 286888, NCBI: NP_775132.1, UniProt: Q8CHN3 |
Catalog # | MBS1752495 |
Price | $280 |
Order / More Info | HE4 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: WFDC2 WAP four-disulfide core domain 2. 2. Hellstrom I, Raycraft J, Hayden-Ledbetter M, Ledbetter JA, Schummer M, McIntosh M, Drescher C, Urban N, Hellstrom KE (2003-07-01). The HE4 (WFDC2) Protein Is a Biomarker for Ovarian Carcinoma. Cancer Research63 (13): 3695-3700. 3. Molina R, Escudero JM, Auge JM, Filella X, Foj L, Torne A, Lejarcegui J, Pahisa J (2011). HE4 a novel tumour marker for ovarian cancer: Comparison with CA 125 and ROMA algorithm in patients with gynaecological diseases. Tumor Biology 32 (6): 1087-95. |