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Antigenic Specificity | CHD3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. |
Immunogen | Immunogen: A synthetic peptide of human CHD3 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [Mi-2a; Mi2-ALPHA; ZFH] |
Gene, Accession # | [CHD3], Gene ID: 1107, NCBI: NP_001005271.2, UniProt: Q12873 |
Catalog # | MBS8535686 |
Price | $300 |
Order / More Info | CHD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |