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Antigenic Specificity | Human Prostaglandin E synthase 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway |
Immunogen | Immunogen: Recombinant human Prostaglandin E synthase 3 protein (1-110aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-66254 / sc-66256 / sc-68399 |
Other Names | [Cytosolic prostaglandin E2 synthase; cPGES; Hsp90 co-chaperone; Progesterone receptor complex p23; Telomerase-binding protein p23; PTGES3; P23; TEBP], [PTGES3; PTGES3; P23; TEBP; cPGES; P23; TEBP; cPGES] |
Gene, Accession # | [PTGES3], Gene ID: 10728, NCBI: NP_001269530.1, UniProt: Q15185 |
Catalog # | MBS1494027 |
Price | $120, $160 |
Order / More Info | Human Prostaglandin E synthase 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |