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Antigenic Specificity | MAGEL2 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, human, porcine, rabbit |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against MAGEL2. It was validated on Western BlotTarget Description: Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAGEL2 |
Other Names | [MAGE-like protein 2; MAGE-like protein 2; MAGE-like protein 2; MAGE family member L2; Necdin-like protein 1; Protein nM15] |
Gene, Accession # | [MAGEL2], Gene ID: 54551, NCBI: Q9UJ55.1, UniProt: Q9UJ55 |
Catalog # | MBS3214557 |
Price | $335 |
Order / More Info | MAGEL2 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |