p63 (Phospho-Ser395) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | p63 (Phospho-Ser395) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of p63 only when phosphorylated at serine 395. Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell com |
| Immunogen | Immunogen Type: peptide Immunogen Description: Peptide sequence around phosphorylation site of serine 395 (R-R-S(p)-P-D) derived from Human p63. |
| Other Names | [EEC3; KET; LMS; p51; p73H; p73L; SHFM4; TA p63 alpha; TP63; tumor protein p63] |
| Gene, Accession # | [p63], Gene ID: 8626, NCBI: NP_001108450.1, UniProt: Q9H3D4 |
| Catalog # | MBS9401208 |
| Price | $200, $255 |
| Order / More Info | p63 (Phospho-Ser395) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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