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Antigenic Specificity | IRGM (C-term), 151-179 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.35 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This IRGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-179 amino acids from the C-terminal region of human IRGM. This gene encodes a member of the p47 immunity-relatedGTPase family. The encoded protein may play a role in the innateimmune response by regulating autophagy formation in response tointracellular pathogens. Polymorphisms that affect the normalexpression of this gene are associated with a susceptibility toCrohn's disease and tuberculosis. |
Immunogen | n/a |
Other Names | [Immunity-related GTPase family M protein; 365-; Immunity-related GTPase family M protein 1; Interferon-inducible protein 1; LPS-stimulated RAW 2647 macrophage protein 47 homolog; LRG-47; IRGM; IFI1; IRGM1; LRG47] |
Gene, Accession # | [IRGM], Gene ID: 345611, NCBI: NP_001139277.1, UniProt: A1A4Y4 |
Catalog # | MBS9201856 |
Price | $165, $370 |
Order / More Info | IRGM (C-term), 151-179 Antibody from MYBIOSOURCE INC. |
Product Specific References | Che, N., et al. Clin. Chim. Acta 411 (21-22), 1645-1649 (2010) : Wolfkamp, S.C., et al. Eur J Gastroenterol Hepatol 22(8):933-937(2010) Latiano, A., et al. Inflamm. Bowel Dis. 16(7):1108-1117(2010) Prescott, N.J., et al. Hum. Mol. Genet. 19(9):1828-1839(2010) Bekpen, C., et al. PLoS Genet. 5 (3), E1000403 (2009) : |