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Antigenic Specificity | CAPZA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CAPZA1 antibody detects endogenous levels of CAPZA1. Function: F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions.Subunit Structure: Heterodimer of an alpha and a beta subunit. Interacts with S100A (By similarity). Component of the WASH complex, composed of F-actin-capping protein subunit alpha (CAPZA1, CAPZA2 or CAPZA3), F-actin-capping protein subunit beta (CAPZB), WASH (WASHC1, WASH2P, WASH3P, WASH4P, WASH5P or WASH6P), WASHC2 (WASHC2A |
Immunogen | Immunogen: A synthesized peptide derived from human CAPZA1. Subcellular Location: Cytoplasm > Cytoskeleton. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (86%) |
Other Names | [Cap Z; Cappa 1; Cappa1; Capping protein (actin filament) muscle Z line alpha 1; Capping protein alpha 1; Capping protein muscle Z line alpha 1; CapZ alpha 1; CapZ alpha-1; CAPZ; CAPZA 1; Capza1; CAZ 1; CAZ1; CAZA1_HUMAN; F actin capping protein alpha 1 subunit; F-actin-capping protein subunit alpha-1] |
Gene, Accession # | [CAPZA1], Gene ID: 829, NCBI: NP_006126.1, UniProt: P52907 |
Catalog # | MBS9603373 |
Price | $240, $280 |
Order / More Info | CAPZA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |