Human ATG12 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman ATG12
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatPeptide Affinity purified
Size0.1 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionATG12 (autophagy-related protein 12), also known as APG12, is a 140 amino acid protein that is ubiquitously expressed and belongs to the ATG12 family of proteins. ATG12 is a homolog of the yeast protein APG12 that participates in autophagy. Autophagy is a membrane trafficking mechanism that delivers cytoplasmic cargo to the vacuole/lysosome for degradation and recycling. In yeast, autophagy requires a protein conjugation system consisting of APG12 covalently bound at the carboxy terminal glycine to lysine 149 of APG5. Similarly in humans, ATG12 is essential for autophagy and localizes to the cytoplasm where it is covalently bound to APG5, a conjugation reaction that requires APG7, ATG10 and ATP (1-3). The ATG12-APG5 conjugate functions as a
ImmunogenImmunogen: Synthetic peptide from the N-terminal of human ATG12. Immunogen Species: Human
Other Names[APG12-like; APG12; ATG12_Human; HAPG12; FBR93; ATG12 : Streptavidin; Rabbit Human ATG12; Rabbit Human ATG12; ATG12], [ATG12; ATG12; APG12; FBR93; APG12L; HAPG12; APG12; APG12L; APG12-like]
Gene, Accession #[ATG12], Gene ID: 9140, NCBI: NP_001264712.1, UniProt: O94817
Catalog #MBS807397
Price$435
Order / More InfoHuman ATG12 Antibody from MYBIOSOURCE INC.
Product Specific References1. Mizushima N., Sugita H., Yoshimori T., Ohsumi Y. (1999) J Biol Chem. 273(51): 33889-33892. 2. Mizushuma N., et al. (1998) Nature. 395: 395-398. 3. Suzuki K., et al. (2001) EMBO J. 20: 5971-5981.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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