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Antigenic Specificity | Human CD54 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml after reconstitution |
Applications | ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human CD54 antibody recognizes human CD54, otherwise known as Intercellular adhesion molecule 1 or ICAM-1. CD54 is a 532 amino acid single pass type I membrane glycoprotein containing five Ig-like C2-type domains. CD54 is widely expressed and acts as a ligand for the leukocyte integrin LFA-1 (CD11a/CD18) and Mac-1 integrins, it is the major receptor for human rhinovirus(Staunton et al. 1989). CD54 is highly expressed on activated endothelial cells (Favoloro 1993) and plays a role in transendothelial cell migration to sites of acute inflammation, functioning primarily as an adhesion molecule between endothelial cells and leucocytes, following injury or stress (Manes and Pober 2011). Levels of soluble CD54 in serum (Matalliotakis |
Immunogen | Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antiserum to human CD54 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Human |
Other Names | [intercellular adhesion molecule 1; Intercellular adhesion molecule 1; intercellular adhesion molecule 1; ICAM-1; cell surface glycoprotein P3.58; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; major group rhinovirus receptor; intercellular adhesion molecule 1; Major group rhinovirus receptor; CD_antigen: CD54], [ICAM1; ICAM1; BB2; CD54; P3.58; ICAM-1] |
Gene, Accession # | [CD54], Gene ID: 3383, NCBI: NP_000192.2, UniProt: P05362 |
Catalog # | MBS224255 |
Price | $550 |
Order / More Info | Human CD54 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |