BRCA1 (pSer1423) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | BRCA1 (pSer1423) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti BRCA1 (pSer1423) antibody recognizes breast cancer type 1 susceptibility protein encoded by BRCA1, also known as RING finger protein 53, when phosphorylated at serine 1423. Breast cancer susceptibility genes BRCA1 and BRCA2 are associated with hereditary breast and ovarian cancers. BRCA1 is a tumor suppressor gene encoding an E3 ubiquitin protein ligase that plays a major role in DNA damage repair (Roy et al. 2011). BRCA1 is also involved in the regulation of multiple processes including transcription and cell cycle progression. BRCA1 is reported to be phosphorylated by ATM and ATR at serine 1423 in response to DNA damage (Tibbetts et al. 2000). |
| Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding serine 1423 of human BRCA1 |
| Other Names | [BRCA1 (pSer1423)], [BRCA1; BRCA1; IRIS; PSCP; BRCAI; BRCC1; FANCS; PNCA4; RNF53; BROVCA1; PPP1R53; RNF53] |
| Gene, Accession # | [BRCA1], Gene ID: 672, NCBI: P38398.2, UniProt: P38398 |
| Catalog # | MBS225199 |
| Price | $375 |
| Order / More Info | BRCA1 (pSer1423) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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