Shank3, 840-857 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Shank3, 840-857 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Shank3, 840-857 |
| Clone | [S69-46] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2b |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Shank3. This antibody recognizes human, mouse, and rat Shank3. It does not cross-react with Shank1 or Shank2. Shank proteins are a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Shank proteins are crucial in receptor tyrosine kinase signaling; specifically, Shank3 can mediate Erk-MAPK and P13K signaling which is crucial for tubule formation. Shank 3 is also one of the latest genes to be associated with autism. A mutation in a single copy of Shank3 on chromosome 22q13 can result in communication disorders. |
| Immunogen | Antigen: Synthetic peptide corresponding to aa 840-857 (PEKLPGSLRKGIPRTKSV) of rat Shank3 (accession no. Q9JLU4). |
| Other Names | [SH3 and multiple ankyrin repeat domains protein 3; SHANK3; SH3 and multiple ankyrin repeat domains protein 3; shank postsynaptic density protein; proline rich synapse associated protein 2; proline-rich synapse-associated protein 2; SH3 and multiple ankyrin repeat domains 3], [SHANK3; SHANK3; PSAP2; SCZD15; PROSAP2; SPANK-2; KIAA1650; DEL22q13.3] |
| Gene, Accession # | Gene ID: 85358, NCBI: NP_001073889.1, UniProt: Q3S3B4 |
| Catalog # | MBS190511 |
| Price | $410 |
| Order / More Info | Shank3, 840-857 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies