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Antigenic Specificity | MYH7-specific |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MYH7-specific antibody detects endogenous levels of MYH7-specific. Function: Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle.Subunit Structure: Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Interacts with ECPAS (PubMed:20682791). Interacts (via C-terminus) with LRRC39 (PubMed:20847312).Similarity: The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 |
Immunogen | Immunogen: A synthesized peptide derived from human MYH7-specific. Subcellular Location: Cytoplasm > Myofibril. Thick filaments of the myofibrils. Tissue Specificity: Both wild type and variant Gln-403 are detected in skeletal muscle (at protein level). Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog Similarity: Pig (92%), Bovine (92%), Horse (100%), Sheep (92%), Dog (100%) |
Other Names | [Beta myosin heavy chain; cardiac muscle beta isoform; CMD1S; CMH1; MPD1; MYH7; MYH7_HUMAN; Myhc slow; MyHC-beta; MyHC-slow; MYHCB; Myopathy, distal 1; Myosin heavy chain (AA 1-96); Myosin heavy chain 7; Myosin heavy chain; Myosin heavy chain slow isoform; Myosin heavy chain, cardiac muscle beta isoform; Myosin, heavy chain 7, cardiac muscle, beta; Myosin, heavy polypeptide 7, cardiac muscle, beta; Myosin-7; Rhabdomyosarcoma antigen MU RMS 40.7A; SPMD; SPMM] |
Gene, Accession # | [MYH7], Gene ID: 4625, NCBI: NP_000248.2, UniProt: P12883 |
Catalog # | MBS9603350 |
Price | $240, $280 |
Order / More Info | MYH7-specific Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |