PITRM1 (Center), 490-518 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PITRM1 (Center), 490-518 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.26 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the Central region of human PITRM1. ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. |
| Immunogen | n/a |
| Other Names | [Presequence protease; mitochondrial; hPreP; 3424-; Pitrilysin metalloproteinase 1; Metalloprotease 1; hMP1; PITRM1; KIAA1104; MP1] |
| Gene, Accession # | [PITRM1], Gene ID: 10531, NCBI: NP_001229236.1, UniProt: Q5JRX3 |
| Catalog # | MBS9207907 |
| Price | $165, $370 |
| Order / More Info | PITRM1 (Center), 490-518 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010) Pinho, C.M., et al. Neurosci. Lett. 469(2):204-208(2010) Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010) Yoshida, T., et al. Int. J. Mol. Med. 24(4):539-547(2009) Chow, K.M., et al. Biochemistry 48(13):2868-2877(2009) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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