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Antigenic Specificity | GAPDH |
Clone | [1D4] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG |
Format | unconjugated |
Size | 0.1 mg, 1 mg |
Concentration | 100ug/100ul |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Clone1D4 is known to react with GAPDH from human, cow, pig, mouse, rat and other mammals, and also recognizes avian GAPDH. This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Studies of a similar protein |
Immunogen | Immunogen: Purified pig GAPDH. |
Other Names | n/a |
Gene, Accession # | [GAPDH] |
Catalog # | MBS416879 |
Price | $230, $1260 |
Order / More Info | GAPDH Antibody from MYBIOSOURCE INC. |
Product Specific References | Shintani-ishida, K et al. MDMA induces cardiac contractile dysfunction through autophagy upregulation and lysosome destabilization in rats. Biochim. Biophys. Acta 1842:691-700 (2014). PubMed: 24491919.Cicchetti, F et al. Mutant huntingtin is present in neuronal grafts in Huntington's disease patients. Ann. Neurol. : (2014). PubMed: 24798518.Shintani-ishida, K et al. MDMA induces cardiac contractile dysfunction through autophagy upregulation and lysosome. Biochim. Biophys. Acta, Mol. Basis. Dis. 5:691-700 (2014). PubMed: 24491919.Cicchetti, F et al. Mutant huntingtin is present in neuronal grafts in huntington disease patients. Ann. Neurol. 1:31-42 (2014). PubMed: 24798518.Smith, GS et al. Nucleus-localized 21.5-kDa myelin basic protein promotes oligodendrocyte proliferation and enhances neurite outgrowth in coculture, unlike the plasma membrane-associated 18.5-kDa isoform. J Neurosci Res. 91 (3):349-362 (2013). DOI: 10.1002/jnr.23166. PubMed: 23184356. Application: Western Blot.New, LA et al. Direct Regulation of Nephrin Tyrosine Phosphorylation by Nck Adaptor Proteins. J Biol Chem 288 (3):1500-1510 (2013). DOI: 10.1074/jbc.M112.439463. Application: Western Blot.Bryand, KF et al. Identification of a divalent metal cation binding site in herpes simplex virus 1 (HSV-1) ICP8 required for HSV replication. J Virol 86 (12):6825-6834 (2012). DOI: 10.1128/JVI.00374-12. Application: Immunoblot.Evans, RP et al. Expression, adverse prognostic significance and therapeutic small molecule inhibition of Polo-like kinase 1 in multiple myeloma. Leuk Res 35 (12):1637-1640 (2011). DOI: 10.1016/j.leukres.2011.07.016. PubMed: 21816470. Application: Immunoblot.Evans, RP et al. The selective Aurora B kinase inhibitor AZD1152 is a potential new treatment for multiple myeloma. Br J Haematol 140 (3):295-302 (2008). PubMed: 18076711. Application: Immunoblot.Evans, RP et al. Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells. Leuk Lymphoma 49 (3):559-569 (2008). DOI: 10.1080/10428190701824544. Application: Immunoblot. |