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Antigenic Specificity | ACVL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ACVL1 protein. Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.ten Dijke P., Oncogene 8:2879-2887(1993).Attisano L., Cell 75:671-680(1993).Berg J.N., Am. J. Hum. Genet. 61:60-67(1997). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human ACVL1. |
Other Names | [ACVL1; ACVRL1; ACVRLK1; ALK-1; Activin receptor-like kinase 1] |
Gene, Accession # | [ACVL1], Gene ID: 94, NCBI: NP_000011.2, UniProt: P37023 |
Catalog # | MBS9404252 |
Price | $200, $255 |
Order / More Info | ACVL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |