ACVL1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityACVL1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous levels of total ACVL1 protein. Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.ten Dijke P., Oncogene 8:2879-2887(1993).Attisano L., Cell 75:671-680(1993).Berg J.N., Am. J. Hum. Genet. 61:60-67(1997).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human ACVL1.
Other Names[ACVL1; ACVRL1; ACVRLK1; ALK-1; Activin receptor-like kinase 1]
Gene, Accession #[ACVL1], Gene ID: 94, NCBI: NP_000011.2, UniProt: P37023
Catalog #MBS9404252
Price$200, $255
Order / More InfoACVL1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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