Edit |   |
---|---|
Antigenic Specificity | CKAP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Cytoskeleton-associated protein 4(Ckap4) detection. Background: Cytoskeleton-associated protein 4, also known as CLIMP63 and p63, is a protein that in humans is encoded by the CKAP4 gene. It is mapped to 12q23.3. CKAP4 is found on the plasma membrane of select cells such as vascular smooth muscle and Type II Greater alveolar lung cells. It has a bimodal distribution. First, CKAP4 is found on the plasma membrane and serves as a receptor for SP-A/surfactant protein-A (in lung) and tPA (in vessels). Second, it is embedded in the membrane of a compartment that links the ER with the Golgi apparatus. This localization is dependent on its ability to form homooligomers, and its presence serves to anchor microtubul |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse CKAP4 (95-118aa LVAAAAFSGWYVHHVLEEVQQVRR), different from the related human sequence by one amino acid. |
Other Names | [CKAP 4; Ckap4; ERGIC 63; ERGIC63; ERGIC-63; p63; Q8BMK4; Cytoskeleton-associated protein 4], [Ckap4; Ckap4; P63; CLIMP-63; 5630400A09Rik; Climp-63; p63] |
Gene, Accession # | [Ckap4], Gene ID: 216197, NCBI: NP_780660.1, UniProt: Q8BMK4 |
Catalog # | MBS178663 |
Price | $280 |
Order / More Info | CKAP4 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: CKAP4 cytoskeleton-associated protein 4.2. Schweizer A, Rohrer J, Jeno P, DeMaio A, Buchman TG, Hauri HP (Jul 1993). A reversibly palmitoylated resident protein (p63) of an ER-Golgi intermediate compartment is related to a circulatory shock resuscitation protein. J Cell Sci. 104 (3): 685-94. |