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Antigenic Specificity | AIRE-1 (Phospho Ser156) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-AIRE-1 (S156) Polyclonal Antibody detects endogenous levels of AIRE-1 protein only when phosphorylated at S156. AIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). |
Immunogen | Immunogen: Synthesized peptide derived from human AIRE-1 around the phosphorylation site of S156 |
Other Names | [Rabbit AIRE-1 (phospho Ser156); AIRE; APECED; Autoimmune regulator; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; APECED protein] |
Gene, Accession # | [AIRE-1], Gene ID: 326, NCBI: NP_000374.1, UniProt: O43918 |
Catalog # | MBS9705411 |
Price | $130, $220, $325 |
Order / More Info | AIRE-1 (Phospho Ser156) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |