Human ULBP2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman ULBP2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionLigand for the KLRK1/NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
ImmunogenImmunogen: Recombinant human NKG2D ligand 2 protein (26-216aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-20569 / sc-33565
Other Names[N2DL-2;NKG2DL2;ALCAN-alpha;Retinoic acid early transcript 1H;UL16-binding protein 2;ULBP2;N2DL2; RAET1H], [ULBP2; ULBP2; N2DL2; RAET1H; NKG2DL2; ALCAN-alpha; N2DL2; RAET1H; N2DL-2; NKG2DL2]
Gene, Accession #[ULBP2], Gene ID: 80328, NCBI: NP_079493.1, UniProt: Q9BZM5
Catalog #MBS1497993
Price$120, $160
Order / More InfoHuman ULBP2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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