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Antigenic Specificity | Plzf |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat. |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Zinc finger and BTB domain-containing protein 16 (ZBTB16) detection. Background: Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene. This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. |
Immunogen | Immunogen: E Coli-derived human Plzf recombinant protein (Position: M1-E165). |
Other Names | [PLZF; ZBTB16; ZBTB 16; Zfp145; Znf145; Q05516; Zinc finger and BTB domain-containing protein 16; zinc finger and BTB domain containing 16], [ZBTB16; ZBTB16; PLZF; ZNF145; PLZF; ZNF145] |
Gene, Accession # | [ZBTB16], Gene ID: 7704, NCBI: NP_001018011.1, UniProt: Q05516 |
Catalog # | MBS178469 |
Price | $280 |
Order / More Info | Plzf Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Kovalovsky D, Uche OU, Eladad S, Hobbs RM, Yi W, Alonzo E, Chua K, Eidson M, et al. (2008). The BTB-zinc finger transcriptional regulator, PLZF, controls the development of iNKT cell effector functions. Nature Immunology 9 (9): 1055-64.2. Savage AK, Constantinides MG, Han J, Picard D, Martin E, Li B, Lantz O, Bendelac A (2008). The transcription factor PLZF (Zbtb16) directs the effector program of the NKT cell lineage.Immunity 29 (3): 391-403.3. Zhang T, Xiong H, Kan LX, Zhang CK, Jiao XF, Fu G, Zhang QH, Lu L, et al. (1999). Genomic sequence, structural organization, molecular evolution, and aberrant rearrangement of promyelocytic leukemia zinc finger gene.Proceedings of the National Academy of Sciences of the United States of America 96 (20): 11422-7. |