UACA / Nucling (Nuclear Membrane Marker) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-UACA / Nucling (Nuclear Membrane Marker) antibody, protein, ELISA kits.
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| Antigenic Specificity | UACA / Nucling (Nuclear Membrane Marker) |
| Clone | [UACA/1222] |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway. |
| Immunogen | Immunogen: Recombinant human UACA protein |
| Other Names | [Nuclear membrane binding protein; Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA); NUCLING], [UACA; UACA; NUCLING; KIAA1561] |
| Gene, Accession # | [UACA], Gene ID: 55075, NCBI: NP_001008225.1, UniProt: Q9BZF9 |
| Catalog # | MBS439068 |
| Price | $190, $340, $340 |
| Order / More Info | UACA / Nucling (Nuclear Membrane Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yamada, K., et al. 2001. Identification of a novel autoantigen UACA in patients with panuveitis. Biochem. Biophys. Res. Commun. 280: 1169-1176. Ohkura, T., et al. 2004. Detection of the novel autoantibody (anti-UACA antibody) in patients with Graves disease. Biochem. Biophys. Res. Commun. 321: 432-440 |
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MYBIOSOURCE INC.
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