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Antigenic Specificity | MEP1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components. |
Immunogen | Immunogen: Recombinant human Meprin A subunit beta protein (480-652AA) |
Other Names | [Meprin A subunit beta; Endopeptidase-2; Meprin B; N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta; PABA peptide hydrolase; PPH beta; MEP1B] |
Gene, Accession # | [MEP1B], Gene ID: 4225, NCBI: NP_001295100.1, UniProt: Q16820 |
Catalog # | MBS7045259 |
Price | $120, $160 |
Order / More Info | MEP1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |