Edit |   |
---|---|
Antigenic Specificity | AGXT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total AGXT protein. Serine!?pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1), also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble cal |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from 280-294 amino acids of human alanine-glyoxylate aminotransferase |
Other Names | [Alanine-glyoxylate aminotransferase, AGT; PH1; SPT; AGT1; SPAT; TLH6; AGXT1] |
Gene, Accession # | [AGXT], Gene ID: 189, NCBI: NP_000021 |
Catalog # | MBS9413137 |
Price | $200, $255 |
Order / More Info | AGXT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |