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Antigenic Specificity | NMDANR2B Subunit |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total NMDANR2B Subunit protein. NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.1250-1254(N-L-Y-D-I) derived from Human NMDANR2B Subunit. |
Other Names | [NMDAR2B; NR2B] |
Gene, Accession # | [NMDANR2B], Gene ID: 24410, NCBI: NP_036706.1, UniProt: Q00960 |
Catalog # | MBS9410761 |
Price | $200, $255 |
Order / More Info | NMDANR2B Subunit Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |