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Antigenic Specificity | CD276 |
Clone | [2009CT652.35.9] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CD276 antibody is generated from a mouse immunized with a recombinant protein from the human region of human CD276. May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhanc |
Immunogen | n/a |
Other Names | [CD276 antigen; 4Ig-B7-H3; B7 homolog 3; B7-H3; Costimulatory molecule; CD276; CD276; B7H3] |
Gene, Accession # | [CD276], Gene ID: 80381, NCBI: CAE47548.1, UniProt: Q5ZPR3 |
Catalog # | MBS9231332 |
Price | $165, $370 |
Order / More Info | CD276 Antibody from MYBIOSOURCE INC. |
Product Specific References | Chapoval A.I.,et al.Nat. Immunol. 2:269-274(2001). Steinberger P.,et al.J. Immunol. 172:2352-2359(2004). Clark H.F.,et al.Genome Res. 13:2265-2270(2003). Ota T.,et al.Nat. Genet. 36:40-45(2004). Otsuki T.,et al.DNA Res. 12:117-126(2005). |