NALP2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNALP2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionNALP2 Antibody: NALP2 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli. Unlike the prototypical NALP protein NALP1, NALP2 only contains a NACHT domain, leucine rich repeat (LRR), and pyrin-containing domain (PYD). This protein interacts with the adapter protein ASC in addition to CARD8 and caspase-1 to form an inflammasome with high proIL-1β-processing activity and is thought to function as a modulator of NF-κB and procaspase-1 activation in macrophages. It has also been suggested that NALP2, in addition to other NALP family members, can act as innate sensors of pathogens in a manner similar to the toll-like receptors (TLRs). At least two alternatively sp
ImmunogenImmunogen: NALP2 antibody was raised against a peptide corresponding to 12 amino acids near the carboxy terminus of human NALP2. Buffer: NALP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[NALP2; NBS1; PAN1; NALP2; PYPAF2; CLR19.9; NBS1; NACHT; LRR and PYD domains-containing protein 2; Nucleotide-binding site protein 1; NLR family, pyrin domain containing 2], [NLRP2; NLRP2; NBS1; PAN1; NALP2; PYPAF2; CLR19.9; NALP2; NBS1; PAN1; PYPAF2]
Gene, Accession #[NLRP2], Gene ID: 55655, NCBI: NP_060322, UniProt: Q9NX02
Catalog #MBS150327
Price$375
Order / More InfoNALP2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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