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Antigenic Specificity | CD22 [hL22 (Epratuzumab)] |
Clone | [hL22 (Epratuzumab] |
Host Species | Human |
Reactive Species | human, rhesus monkey, cynomolgus monkey |
Isotype | IgG1, kappa |
Format | Protein A purified |
Size | 0.2 mg |
Concentration | n/a |
Applications | Blocking, Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is specific for the 3rd Ig-like domain of human CD22 (epitope B), a cellsurface glycoprotein present on mature B-cells and on many types of malignant B-cells. Recombinant monoclonal antibody to CD22. Manufactured using Recombinant Platform with variable regions (i.e. specificity) from the hybridoma hL22 (Epratuzumab). |
Immunogen | Immunogen: This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5-10% of the molecule, with the remainder being human frame work sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010). Antigen: CD22. Antigen Description: This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequen |
Other Names | [B-cell receptor CD22; B-lymphocyte cell adhesion molecule; BL-CAM; Sialic acid-binding Ig-like lectin 2; Siglec-2; T-cell surface antigen Leu-14], [CD22; CD22; SIGLEC2; SIGLEC-2; SIGLEC2; BL-CAM; Siglec-2] |
Gene, Accession # | [CD22], Gene ID: 933, NCBI: BAA36576.1 |
Catalog # | MBS488271 |
Price | $425 |
Order / More Info | CD22 [hL22 (Epratuzumab)] Antibody from MYBIOSOURCE INC. |
Product Specific References | Pawlak-Byczkowska et al., Leung et al. Cancer research, 15 August 1989, Vol.49(16), pp.4568-77 &Molecular Immunology, 1995, Vol.32(17), pp.1413-1427 |