Edit |   |
Antigenic Specificity | liver Arginase |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | rat. predicted to work with: human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Arginase-1(ARG1) detection. Tested with WB in Human;Rat. Background: ARG1 (arginase, live) is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. The isoform encoded by ARG1, referred to as the liver, or A-I, isoform, contributes 98% of the arginase activity in liver but is also present in red cells. Using a rat liver ARG1 cDNA clone to probe a human liver cDNA library, Haraguchi et al. (1987) isolated and characterized a cDNA corresponding to the ARG1 gene. The ARG1 gene is mapped on 6q23.2 and the arginase gene contains 8 exons. By immunologic studies, 90% of the arginase in red blood cell and liver was precipitated by the antibody, whereas only 50% |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human liver Arginase (64-92aa FQIVKNPRSVGKASEQLAGKVAEVKKNGR), different from the related mouse sequence by four amino acids, and from the related rat sequence by five amino acids. Ig Type: Rabbit IgG |
Other Names | [Arginase-1; A I; Al; ARG 1; ARG1; ARGI1_HUMAN; Arginase 1; Arginase liver; Arginase type I; Arginase-1; Arginase1; Liver type arginase; Liver-type arginase; Type I arginase; arginase, liver], [ARG1; ARG1] |
Gene, Accession # | Gene ID: 383, NCBI: NP_000036.2, UniProt: P05089 |
Catalog # | MBS178314 |
Price | $280 |
Order / More Info | liver Arginase Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Cardoso, M. L., Martins, E., Vasconcelos, R., Vilarinho, L., Rocha, J. Identification of a novel R21X mutation in the liver-type arginase gene (ARG1) in four Portuguese patients with argininemia. Hum. Mutat. 14: 355-356, 1999. 2. Grody, W. W., Dodson, A., Klein, D., Kern, R. M., Bassand, P., Cederbaum, S. D. Molecular genetic study of human arginase deficiency. (Abstract) Am. J. Hum. Genet. 45 (suppl.): A191 only, 1989. 3. Haraguchi, Y., Takiguchi, M., Amaya, Y., Kawamoto, S., Matsuda, I., Mori, M. Molecular cloning and nucleotide sequence of cDNA for human liver arginase. Proc. Nat. Acad. Sci. 84: 412-415, 1987. |